Langzeitbetreuung nach Organtransplantation

Zusammenfassung

Die Überlebensraten nach Organtransplantation sind aufgrund von Fortschritten in der immunsuppressiven Therapie und Verbesserung der chirurgischen Technik in den letzten Jahrzehnten stetig gestiegen. In der Langzeitnachsorge nach Organtransplantation sind sowohl die Diagnose und Behandlung Transplantat-assoziierter Komplikationen als auch die Berücksichtigung von Begleiterkrankungen und Nebenwirkungen der Immunsuppression relevant, um Folgeerkrankungen zu verhindern. Insbesondere kardiovaskuläre und metabolische Erkrankungen sowie Tumorerkrankungen spielen im Langzeitverlauf eine große Rolle. Daher sind Screening-Untersuchungen auf eben diese häufigen Komplikationen ein zentraler Bestandteil der Langzeitnachsorge.

Abstract

Due to advances in immunosuppressive therapy and surgical techniques, survival rates after solid organ transplantation have constantly improved over the last decades. In long-term care after transplantation, physicians need to focus as much on diagnosis and treatment of allograft-related complications as they should consider comorbidities and evaluate risk-factors and adverse events of immunosuppressive agents to prevent secondary diseases. In particular, cardiovascular and metabolic diseases, malignancy and infection play a major role in long-term survival. Therefore, screening of organ transplant recipients in regard to these complications and adverse events is a crucial part of follow up in these patients.

Schlüsselwörter

Organtransplantation - Langzeitbetreuung - Immunsuppression - Begleiterkrankungen

Keywords

solid-organ-transplantation - long-term-management - immunosuppression - comorbidities

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